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Pharmaceutical compound
5-MeO-MsBT
Clinical data
Other names5-MeO-MSBT; 5-Methoxy-N-methyl-N-sec-butyltryptamine
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action3–4 hours[1]
Identifiers
  • N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-methylbutan-2-amine
PubChem CID
Chemical and physical data
FormulaC16H24N2O
Molar mass260.381 g·mol−1
3D model (JSmol)
  • CCC(C)N(C)CCC1=CNC2=C1C=C(C=C2)OC
  • InChI=1S/C16H24N2O/c1-5-12(2)18(3)9-8-13-11-17-16-7-6-14(19-4)10-15(13)16/h6-7,10-12,17H,5,8-9H2,1-4H3
  • Key:VBRYRPHGPPNPMK-UHFFFAOYSA-N

5-MeO-MsBT, also known as 5-methoxy-N-methyl-N-sec-butyltryptamine, is a psychedelic drug of the tryptamine and 5-methoxytryptamine families.[1][2] It emerged as a novel designer drug online in December 2022.[1] More specifically, its chemical synthesis and the claimed properties and effects of 5-MeO-MsBT were posted on a specialized psychoactive drug forum.[1]

The dose of the drug is said to be 10 to 30 mg orally and its duration is said to be 3 to 4 hours.[1] Its effects were reported to include a tryptamine-like warmth or fuzzy feeling, tactile and music enhancement, enhanced mood, confusion, mild paranoia, weak psychedelic effects and self-detachment at higher doses, and an antidepressant-like psychedelic afterglow.[1] The afterglow is said to last 12 to 24 hours, with apparent tolerance developing to it with repeated administration over a few days.[1] 5-MeO-MsBT's effects were described as very similar to those of 5-MeO-MiPT at lower doses, but it is less potent than 5-MeO-MiPT and was regarded as inferior in many respects.[1]

The drug has not otherwise been encountered, for instance sold online or in drug seizures, as of 2023.[1] It is not a controlled substance in Canada as of 2025.[3] The drug is not an explicitly controlled substance in the United States,[4] but could be considered a controlled substance under the Federal Analogue Act if intended for human consumption.

See also

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References

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  1. 1 2 3 4 5 6 7 8 9 10 "5-MeO-MsBT (5-methoxy-N-methyl-N-secbutyltryptamine)". AIPSIN (in Russian). Retrieved 2 January 2026.
  2. ↑ Yurchenko R, Yurchenko L, Pavlovets Y, Galetskaya I (January 2023). "Recent trends in the identification of psychoactive substances". AIPSIN Belarusian monitoring platform (in Russian). doi:10.13140/RG.2.2.34396.46722. Retrieved 2 January 2026.
  3. ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
  4. ↑ Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026) (PDF), United States: U.S. Department of Justice: Drug Enforcement Administration (DEA): Diversion Control Division, January 2026
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