Ganesha (psychedelic)

Ganesha
Clinical data
Other names	GANESHA; G; G-0; 3C-G; 3,4-Dimethyl-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-dimethylamphetamine; 3-Methyl-DOM; 3-Me-DOM; DOG; DOG-0
Routes of; administration	Oral
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None;
Pharmacokinetic data
Onset of action	Slow over 3 hours or rapid
Duration of action	18–24 hours
Identifiers
	IUPAC name 1-(2,5-dimethoxy-3,4-dimethylphenyl)propan-2-amine;
CAS Number	207740-37-2 Y;
PubChem CID	44350044;
ChemSpider	21106315 Y;
UNII	255K39NLR7;
ChEMBL	ChEMBL339431 Y;
CompTox Dashboard (EPA)	DTXSID10658374 ;
Chemical and physical data
Formula	C13H21NO2
Molar mass	223.316 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1c(C)c(C)c(cc1CC(C)N)OC;
	InChI InChI=1S/C13H21NO2/c1-8(14)6-11-7-12(15-4)9(2)10(3)13(11)16-5/h7-8H,6,14H2,1-5H3 Y; Key:RBZXVDSILZXPDM-UHFFFAOYSA-N Y;
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Psychedelic drug

Pharmaceutical compound

Ganesha (G or G-0), also known as 3,4-dimethyl-2,5-dimethoxyamphetamine or as 3-methyl-DOM, is a psychedelic drug of the phenethylamine, amphetamine, and DOx families.^[1] It is the 3-methyl derivative of DOM and the amphetamine (α-methyl) derivative of 2C-G.^[1] The drug is taken orally.^[1]

Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists Ganesha's dose range as 24 to 32 mg orally and its duration as 18 to 24 hours.^[1] The drug's onset was variably described as slow over the course of 3 hours or as rapid.^[1] The effects of Ganesha have been reported to include strong closed-eye visuals, an increased appreciation of music, and powerful relaxation and tranquility, among others.^[1] Shulgin named Ganesha after the Hindu deity, Ganesha.^[1] It is one of his "ten classic ladies", a series of methylated DOM derivatives.^[1]^[2]

The chemical synthesis of Ganesha has been described.^[1]

Homologues of Ganesha (G-0) include G-3, G-4, G-5, and G-N, among others.^[1]

Compound	Details	Structure
G-3	CAS #: 207740-36-1 Dose: 12–18 mg Duration: 8–12 hours Effects: Closed-eye imagery, no visuals, fantasy, no body load, neurological sensitivity, others 2C analogue: 2C-G-3
G-4	CAS #: Unknown Partially synthesized but not tested. 2C analogue: 2C-G-4
G-5	CAS #: 133787-68-5 Dose: 14–20 mg Duration: 16–30 hours Effects: No visuals or other sensory effects, excellent mental activity, mental integration, lacking something important, little or no body load 2C analogue: 2C-G-5
G-N	CAS #: 477904-62-4 Synthesized and tested at 2 mg but not up to active levels 2C analogue: 2C-G-N
G-O^[3]	CAS #: 774538-38-4 Described and/or synthesized but not tested 2C analogue: None

Ganesha was first described in the literature by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved) in 1991.^[1]

Ganesha is a controlled substance in Canada under phenethylamine blanket-ban language.^[4]

Ganesha is not an explicitly controlled substance in the United States.^[6] However, it could be considered a controlled substance under the Federal Analogue Act if intended for human consumption. In addition, the drug may considered a controlled substance as a positional isomer of DOET.^[6]^[7]

Clinical data


Other names	GANESHA; G; G-0; 3C-G; 3,4-Dimethyl-2,5-dimethoxyamphetamine; 2,5-Dimethoxy-3,4-dimethylamphetamine; 3-Methyl-DOM; 3-Me-DOM; DOG; DOG-0
Routes of administration	Oral^[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Pharmacokinetic data
Onset of action	Slow over 3 hours or rapid^[1]
Duration of action	18–24 hours^[1]
Identifiers
IUPAC name 1-(2,5-dimethoxy-3,4-dimethylphenyl)propan-2-amine
CAS Number	207740-37-2^Y
PubChem CID	44350044
ChemSpider	21106315^Y
UNII	255K39NLR7
ChEMBL	ChEMBL339431^Y
CompTox Dashboard (EPA)	DTXSID10658374
Chemical and physical data
Formula	C₁₃H₂₁NO₂
Molar mass	223.316 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES COc1c(C)c(C)c(cc1CC(C)N)OC
InChI InChI=1S/C13H21NO2/c1-8(14)6-11-7-12(15-4)9(2)10(3)13(11)16-5/h7-8H,6,14H2,1-5H3^Y Key:RBZXVDSILZXPDM-UHFFFAOYSA-N^Y
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