T-1152

T-1152
Names
	Other names TL-1178; Stedman's meta compound;
Identifiers
CAS Number	3983-39-9 Y;
3D model (JSmol)	Interactive image;
ChemSpider	18732;
PubChem CID	19886;
UNII	7KPX8SZ9L6 Y;
CompTox Dashboard (EPA)	DTXSID60960393;
	InChI InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1H Key: MIAARRZWMRMHIS-UHFFFAOYSA-N;
	SMILES CNC(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[I-];
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	270 μg/kg (subcutaneous, mice); 115 μg/kg (intravenous, mice); 260 μg/kg (subcutaneous, rabbits)
LDLo (lowest published)	2.5 mg/kg (oral, mice)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chemical compound

T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide.^[3] Since T-1152 is toxic by ingestion, it was patented as a rodenticide in 1932.^[2]

The chloride and methylsulfate salt of T-1152 is T-1690 (TL-1226) and AR-13, respectively.^[1]

References

Names

Other names TL-1178 Stedman's meta compound
Identifiers
CAS Number	3983-39-9^Y
3D model (JSmol)	Interactive image
ChemSpider	18732
PubChem CID	19886
UNII	7KPX8SZ9L6^Y
CompTox Dashboard (EPA)	DTXSID60960393
InChI InChI=1S/C11H16N2O2.HI/c1-12-11(14)15-10-7-5-6-9(8-10)13(2,3)4;/h5-8H,1-4H3;1H Key: MIAARRZWMRMHIS-UHFFFAOYSA-N
SMILES CNC(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[I-]
Hazards
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	270 μg/kg (subcutaneous, mice)^[1] 115 μg/kg (intravenous, mice)^[1] 260 μg/kg (subcutaneous, rabbits)^[1]
LD_Lo (lowest published)	2.5 mg/kg (oral, mice)^[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references