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Abstract
According to indicator dilution theory tissue time-concentration curves have to be deconvolved with arterial input curves in order to get valid perfusion results. Our aim was to adapt and validate a deconvolution method originating from magnetic resonance techniques and apply it to the calculation of dynamic contrast enhanced computed tomography perfusion imaging. The application of a block-circulant matrix approach for singular value decomposition renders the analysis independent of tracer arrival time to improve the results.
MeSH terms
- Aged
- Blood Flow Velocity
- Brain / blood supply*
- Brain / diagnostic imaging*
- Contrast Media
- Dye Dilution Technique
- Female
- Humans
- Image Interpretation, Computer-Assisted / methods
- Magnetic Resonance Imaging
- Male
- Mathematical Computing*
- Middle Aged
- Perfusion
- Tomography, X-Ray Computed / methods
Substances
- Contrast Media
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