The re module now depends on the enum module, and the latter already depends on OrderedDict. Thus the patch doesn't introduce new dependency. Python implementation of OrderedDict doesn't override __getitem__ and therefore don't slow down the common case. I considered all this.
In contrary, Python implementation of lru_cache slows down the code (that is why using it was dropped in the past). But I did not object to this because re.sub() is less used than re.match() or re.search() and already is much slower.