Sadly, I can't reproduce the speedups OP reported from disabling test_patma.TestTracing. It's not any faster than what we have with PR28475. (See attached pyperformance).
I'm looking forward to their other fix :). Even if it comes in 3.10.1 that's still a huge win. I don't think everyone immediately upgrades when a new Python version arrives.
IMO, we should note in What's New that only for Windows, 3.10.0 has a slight slowdown. Some use cases are slower (by >10%!), while some people won't feel a thing. (Then again, maybe this is offset by the LOAD_ATTR opcache in 3.10 and we get a net zero effect?). I'll submit a PR soon if the full fix misses 3.10.0.